MK-677, also known as Ibutamoren, is an oral growth hormone secretagogue that stimulates the body’s natural release of growth hormone (GH) and increases levels of insulin-like growth factor 1 (IGF-1). Unlike injectable growth hormone therapies, MK-677 is taken orally and works by activating ghrelin receptors that signal the pituitary gland to release growth hormone.
Because MK-677 enhances endogenous GH production rather than replacing it, it has been studied for its potential role in supporting muscle mass, metabolic health, sleep quality, bone density, and recovery. At BHRT Delivered, MK-677 may be considered as part of a medically supervised hormone optimization or longevity-focused treatment plan.
When used under medical supervision and combined with lifestyle strategies, AOD 9604 may support:
By increasing GH and IGF-1 levels, MK-677 supports muscle protein synthesis and recovery. This may help preserve or increase lean muscle mass and strength, particularly in individuals experiencing age-related decline.
Growth hormone plays a role in fat utilization. MK-677 may support improved body composition by enhancing metabolic efficiency and fat oxidation when combined with appropriate nutrition and activity.
MK-677 has been associated with improvements in sleep quality, particularly deeper sleep stages that are important for recovery, hormone regulation, and overall health.
Increased growth hormone activity may support collagen production and tissue repair, which can contribute to healthier skin and hair over time.
Growth hormone is involved in bone remodeling and density maintenance. MK-677 may help support bone strength, especially in individuals at risk for age-related bone loss.
MK-677 may be appropriate for individuals seeking medically guided support for growth hormone optimization, recovery, or age-related hormonal decline. It may be considered for those who:
Are experiencing reduced muscle mass or strength
Want to support metabolic efficiency and body composition
Have poor sleep quality or impaired recovery
Are concerned about bone density or long-term skeletal health
All patients must be evaluated by a licensed medical provider to determine whether MK-677 is safe and appropriate for their individual health profile.
All patients must undergo medical evaluation to determine appropriateness and safety.
MK-677 has been studied for potential use in several hormone- and age-related conditions, including:
MK-677 may help stimulate endogenous growth hormone production in individuals with low GH levels.
Age-related loss of muscle mass and strength may be mitigated by supporting growth hormone and IGF-1 activity under medical supervision.
By supporting bone metabolism and density, MK-677 may offer benefit as part of a broader bone health strategy.
Improved sleep architecture associated with MK-677 may help individuals struggling with poor sleep quality or recovery.
Before considering prescription therapy, foundational lifestyle strategies may help support natural growth hormone production:
Resistance training and high-intensity exercise are known to naturally stimulate growth hormone release.
Consume adequate protein, healthy fats, and micronutrients to support hormone production and tissue repair.
Chronic stress can suppress hormone production. Stress-reduction techniques such as mindfulness or breathwork may be beneficial.
Prioritize consistent, high-quality sleep, as growth hormone secretion is closely tied to deep sleep stages.
Certain supplements may support sleep or recovery; however, all supplements should be discussed with a healthcare provider before use.
At BHRT Delivered, we use a personalized, medical approach to determine whether MK-677 is appropriate for you.
Your provider will review your medical history, symptoms, medications, and health goals
When appropriate, lab testing may be used to evaluate growth hormone–related markers and overall hormonal balance.
Your provider will discuss potential benefits, risks, and expectations to help you make an informed decision.
Patients receiving MK-677 are monitored throughout treatment to assess effectiveness, safety, and overall response, with adjustments made as needed.
MK-677 is an orally administered growth hormone secretagogue with growing research interest in muscle preservation, metabolic health, sleep quality, bone density, and healthy aging. When used under medical supervision, it may be a valuable component of a comprehensive hormone optimization or longevity-focused care plan.
Through convenient telehealth care, BHRT Delivered provides personalized, evidence-based treatment options designed to support long-term vitality, recovery, and overall well-being.
