Tesofensine is an advanced weight management medication originally developed for neurological conditions such as Parkinson’s and Alzheimer’s disease. During clinical research, it was found to produce significant and consistent weight loss, leading to its use in obesity and metabolic health treatment.
Tesofensine works by inhibiting the reuptake of key neurotransmitters—dopamine, serotonin, and norepinephrine—which are involved in appetite regulation, satiety, and energy balance. By acting on these pathways, Tesofensine helps reduce hunger, curb cravings, and increase overall energy expenditure.
Tesofensine has demonstrated strong weight loss outcomes in clinical studies. Many patients experience meaningful reductions in body weight, with some research showing up to a 10% decrease in total body weight over a six-month period when combined with lifestyle changes.
One of Tesofensine’s primary effects is appetite control. By influencing central hunger pathways, it helps reduce persistent hunger and food cravings, making it easier to maintain a calorie-controlled nutrition plan.
Weight loss achieved with Tesofensine may lead to improvements in metabolic markers such as blood sugar, cholesterol levels, and blood pressure. These improvements can lower the risk of developing chronic conditions like type 2 diabetes and cardiovascular disease.
Many patients report increased energy while taking Tesofensine. Improved energy levels can support greater physical activity, improved consistency with healthy habits, and better overall weight loss outcomes.
Tesofensine may be appropriate for individuals who have struggled to achieve sustainable weight loss through diet and exercise alone. It may be especially beneficial for those who:
Have a body mass index (BMI) of 30 or higher
Have a BMI of 27 or higher with weight-related conditions such as high blood pressure, type 2 diabetes, or sleep apnea
Prefer a targeted, non-stimulant metabolic therapy
Are committed to making long-term lifestyle changes alongside medical treatment
All patients are evaluated by a licensed medical provider to determine if Tesofensine is safe and appropriate.
While Tesofensine is prescribed for weight management, weight reduction may positively impact several obesity-related conditions, including:
Weight loss can improve insulin sensitivity and blood sugar control
Reducing body weight may help lower blood pressure and cardiovascular risk
Improvements in cholesterol and triglyceride levels may occur with weight loss
Weight reduction can lessen the severity of obstructive sleep apnea symptoms
Before starting prescription weight loss therapy, foundational lifestyle strategies are often recommended:
Aim for consistent movement that can be maintained long term. A combination of cardiovascular exercise and strength training is often recommended to support fat loss and metabolic function.
Focus on whole, nutrient-dense foods such as lean proteins, vegetables, fruits, whole grains, and healthy fats. Limiting ultra-processed foods and added sugars can support weight and metabolic health
Practice mindful eating by paying attention to hunger and fullness cues, slowing down during meals, and minimizing distractions while eating.
Chronic stress can interfere with hormones and weight regulation. Techniques such as deep breathing, meditation, stretching, or establishing daily routines may help support overall health.
Poor sleep is closely linked to weight gain and insulin resistance. Aim for 7–9 hours of quality sleep per night by maintaining a consistent sleep schedule and optimizing your sleep environment.
At BHRT Delivered, we take a personalized, medical approach to weight management and metabolic health.
We begin with a detailed review of your medical history, current health status, medications, and weight management goals to determine whether Tesofensine may be appropriate for you.
During your virtual consultation, a licensed medical provider will discuss your symptoms, lifestyle habits, and previous weight loss efforts. This allows us to understand your needs and create an individualized plan.
When appropriate, diagnostic testing may be recommended to assess metabolic markers, hormone balance, or other underlying factors that can influence weight loss results.
We believe in shared decision-making. Your provider will review the potential benefits, risks, and expectations of Tesofensine so you can make an informed decision about treatment.
If Tesofensine is prescribed, we provide ongoing monitoring and support throughout your treatment. Your provider will track progress, address concerns, and make adjustments as needed to support safe and effective results.
Tesofensine offers a medically guided option for individuals struggling with weight management, particularly when lifestyle changes alone have not produced desired results. Through personalized telehealth care, BHRT Delivered provides evidence-based treatment plans designed to support sustainable weight loss, improved metabolic health, and long-term success.
If you are exploring Tesofensine or other weight management solutions, BHRT Delivered offers convenient, clinician-led care focused on safety, results, and whole-body health.
